Search results for " penalized regression"
showing 5 items of 5 documents
Estimation of Granger causality through Artificial Neural Networks: applications to physiological systems and chaotic electronic oscillators
2021
One of the most challenging problems in the study of complex dynamical systems is to find the statistical interdependencies among the system components. Granger causality (GC) represents one of the most employed approaches, based on modeling the system dynamics with a linear vector autoregressive (VAR) model and on evaluating the information flow between two processes in terms of prediction error variances. In its most advanced setting, GC analysis is performed through a state-space (SS) representation of the VAR model that allows to compute both conditional and unconditional forms of GC by solving only one regression problem. While this problem is typically solved through Ordinary Least Sq…
Regularized Regression Incorporating Network Information: Simultaneous Estimation of Covariate Coefficients and Connection Signs
2014
We develop an algorithm that incorporates network information into regression settings. It simultaneously estimates the covariate coefficients and the signs of the network connections (i.e. whether the connections are of an activating or of a repressing type). For the coefficient estimation steps an additional penalty is set on top of the lasso penalty, similarly to Li and Li (2008). We develop a fast implementation for the new method based on coordinate descent. Furthermore, we show how the new methods can be applied to time-to-event data. The new method yields good results in simulation studies concerning sensitivity and specificity of non-zero covariate coefficients, estimation of networ…
Using differential LARS algorithm to study the expression profile of a sample of patients with latex-fruit syndrome
2010
Natural rubber latex IgE-mediated hypersensitivity is one of the most important health problems in allergy during recent years. The prevalence of individuals allergic to latex shows an associated hypersensitivity to some plant-derived foods, especially freshly consumed fruit. This association of latex allergy and allergy to plant-derived foods is called latex-fruit syndrome. The aim of this study is to use the differential geometric generalization of the LARS algorithm to identify candidate genes that may be associated with the pathogenesis of allergy to latex or vegetable food.
Using differential geometric LARS algorithm to study the expression profile of a sample of patients with latex-fruit syndrome
2011
Natural rubber latex IgE-mediated hypersensitivity is one of the most important health problems in allergy during recent years. The prevalence of individuals allergic to latex shows an associated hypersensitivity to some plant-derived foods, especially freshly consumed fruit. This association of latex allergy and allergy to plant-derived foods is called latex-fruit syndrome. The aim of this study is to use the differential geometric generalization of the LARS algorithm to identify candidate genes that may be associated with the pathogenesis of allergy to latex or vegetable.
Information Transfer in Linear Multivariate Processes Assessed through Penalized Regression Techniques: Validation and Application to Physiological N…
2020
The framework of information dynamics allows the dissection of the information processed in a network of multiple interacting dynamical systems into meaningful elements of computation that quantify the information generated in a target system, stored in it, transferred to it from one or more source systems, and modified in a synergistic or redundant way. The concepts of information transfer and modification have been recently formulated in the context of linear parametric modeling of vector stochastic processes, linking them to the notion of Granger causality and providing efficient tools for their computation based on the state&ndash